STE TECPHARM

The OPTIMA TABLET COATER is a perforated coating pan designed for the film coating of tablets or pellets, suitable in aqueous and organic coatings, for the pharmaceutical industry. PATENTED COATING TECHNOLOGY THAT INCREASES THE BATCH SIZE RANGE FROM 10% TO 100% AND OPTIMIZES THE PARAMETER ADJUSTMENT FULLY AUTOMATICALLY. Its high technology allows an automatic adjustment control of the flow, avoiding the damp, saving coating and optimizing the processing time. Innovative high-quality equipment certified by accredited entities. Fully designed and built in Europe following regulatory requirements and GMP´s normative. The OPTIMA TABLET COATER controls each critical variable which is decisive for the dynamic equilibrium, such as: ■ Applied liquid flow. ■ Inlet airflow. ■ Exhaust airflow. ■ Inlet and exit air temperature. ■ Tablet temperature during the process. ■ Turning the speed of the pan drum.

The Granulation Line integrates into a single frame and control panel all options for solid forms production process: ■ Mixing and Granulation: High Shear Granulator. ■ Drying: Fluidized Bed Dryer. ■ Calibration: Conical and Cylindrical Calibrators. It minimizes the space requested in clean-room, reduces the risks of cross-contamination, and gives maximum versatility to process development and scalability studies.

The High Shear Mixer Granulator is designed to optimize the wet granulation process. Used to turn a fine-powder heterogeneous mixture into a uniform granulation, with increased particle size and higher density, offering proper flow and compactness properties, in a short time process and with repeatability. Innovative high-quality equipment certified by accredited entities. Fully designed and built in Europe following regulatory requirements and the GMP´s normative. MAIN FEATURES ■ Standard equipment with capacities ranging from 25 L to 1.400 L. [Other dimensions on request]. ■ In-wall design to be integrated into the cleanroom. ■ Manufactured in AISI 316L. ■ Mirror polished Ra < 0,5. ■ No contact top cover without supports in the container. ■ Bottom impeller and side chopper to guarantee the intensive mixing in a very short time period. ■ Control of endpoint by time or by Torque. ■ PLC + HMI for the control in manual and automatic mode, with recipe editing.

Fluidized Bed Dryer designed for 3 different processes: ■ Drying of wet granulate (dryer). ■ Top drive granulation (granulator). ■ Bottom spray coating (coater). Innovative high-quality equipment certified by accredited entities. Fully designed and built in Europe following regulatory requirements and GMP´s normative. STE TECPHARM offers all range of services: installation “turnkey concept” in the client facilities, start-up, qualification, training, and production support. MAIN FEATURES ■ From 30 L to 1.540 L. [Other dimensions on request]. ■ In-wall design concept. ■ Built-in AISI 316L, mirror polished Ra < 0,5. ■ PCL + HMI in manual and automatic mode, with recipe editing. ■ 12 bar pressure-shock resistance.