Biotechnologies - Import export

The step from the laboratory to manufacturing for clinical trials is a major challenge. Simple hand movements in the laboratory often cannot be easily translated into process steps of industrial manufacturing. We are specialised in such scale ups. Contact us for an initial discussion! Analysis We prepare your laboratory data and compare it with the possible process parameters at the contract manufacturer. If data or optimisations are still missing. We develop the test plan for this. We carry out certain scale-up trials (non GMP) at our technical centre. We accompany specific trials (e.g. with your API) on your premises or those of a plant manufacturer. Models and simulation From the data, we generate the process models you need for scaling up. You will also need these models for the submission documents. We use the data to simulate different scale-up concepts. So if you later transfer from the special CDMO for clinical production to the CDMO for commercial production

Ascopin is designed to ensure a quick and regular start or to catch-up growth, especially during difficult periods or under adverse climatic conditions. Our product helps coniferous trees to overcome stressful conditions (cold, drought, lack or excess of water) which penalize settlement and thus, their quality. Ascopin can be used as a preventive and/or curative treatment and under stressful conditions.

Asco Mn prevents, corrects Manganese deficiencies and stimulates plants growth. Asco Mn is a Biostimulant for agriculture application made with our micronized seaweed extract TSL292 and implemented for the performance of crops which suffer from manganese deficiencies.

Ascoleg is a Biostimulant for crop nutrition. It is specifically formulated for fruit trees and vegetable crops. By activating nutrition and flowering, it secures the fruit set and improves fruit size. Ascoleg is approved for organic agriculture in compliance with regulation (EC) N°834/2007.

Vitavigne is a fertilizer high in Phosphorous, Potassium, Magnesium, Manganese and Molybdenum. It supplies numerous bio-available trace elements in order to guarantee continuous and sustainable growth. It stimulates and regulates plants’ development and improves their resistance ability in times of stress (low temperatures, water deficit...). It also promotes the absorption of soil minerals by crops.

Ascogreen special lawn 27-0-0 start is a liquid fertilizer especially manufactured for lawn. It is made up of micronized seaweed cream TSL29 and enriched with Nitrogen in different forms. It can be used for any types of lawns at any time in the year. In addition to Nitrogen input, it strengthens lawns thanks to rapidly available trace elements and the benefits of seaweeds. At the moment of operation, Ascogreen can be blended with numerous phytosanitary treatments.

Fructicitrus is a soluble NPK fertilizer for agriculture application made with our seaweed extract, TSL292. Its meticulous in-house formulation ensures 100% solubility and excellent roots and leaves uptake. Fructicitrus contains essential minerals and trace-elements. This product can be applied directly on the soil but also sprayed on leaves.

We plan and perform your complete process validation. From the first gap analysis and risk management, planning, execution and reporting. We support you with full project management, providing support where needed. You free your ressources for your projects, we take care for validations and all connected activities. You reach your goals safely, quicker and faster.

Asco AA is a Biostimulant for agriculture application made with our micronized seaweed cream, TSL29, enriched with amino acids. Its meticulous in-house formulation ensures 100% solubility and excellent roots and leaves uptake. Asco AA contains amino acids, essential minerals and trace-elements. This product can be applied directly on the soil but also sprayed on leaves. This product is approved for organic agriculture in compliance with regulation (EC) N°834/2007.

Algostar is a Biostimulant especially designed for cereals and made with our micronized seaweed cream enriched with amino acids TSL293. Its meticulous in-house formulation ensures 100% solubility and excellent roots and leaves uptake. Algostar contains amino acids, essential minerals and trace-elements.

Algolive is a Biostimulant especially made from our micronized algae cream TSL29 and enriched with nitrogen, phosphorous and potassium. Algolive contains essential minerals and trace elements. This product can be applied directly on the soil but also sprayed on leaves.

AlgoBMo is a Biostimulant especially formulated for oilseed crops nutrition. Thanks to its unique formula, it supports the absorption of minerals which are necessary for the development of crops.

Freeze-drying is an important process for preserving and formulating pharmaceutical and biotechnological active ingredients. If an existing process is changed or transferred, the entire cycle must be modified. We advise on the adaptation of a freeze-drying cycle or scale up. Contact us for an initial discussion! Analysis We analyse existing data, model the process and verify the settings before the conversion. For them, this means: high transfer security, short project times, low overall costs. Adaptation of a freeze drying How do we go about it? For the time being, we analyse all existing data and "build" a model of freeze drying from it. The model is based on the physical principles and the real data of their current plant. Consequently, our predictions and forecasts are accurate. From the model, we obtain the settings for the new freeze-drying process. Before the step into production, these settings are verified with a small system.

Algi BZn is a fertiliser formulated from a brown seaweed extract, TSL292, enriched in Boron and Zinc. Its meticulous in-house formulation ensures 100% solubility and excellent roots and leaves uptake. Especially designed for fruits, vegetable crops and vine, Algi BZn contains essential minerals and trace-elements. This product can be applied directly on the soil but also sprayed on leaves. This product is approved for organic agriculture in compliance with regulation (EC) N°834/2007.

TSL292 is a micronized seaweed extract. This growth promoter is an active ingredient specifically formulated for crop treatments by foliar, hydroponic and/or seed applications. Extracted from marine brown seaweed, issued from Brittany coasts, through Biochemistry in-house technology, TSL29 contains growth hormones, amino acids, betaines, oligosaccharides and essential trace elements. This product is approved for organic agriculture in compliance with regulation (EC) N°834/2007. MA N° 1200252

TSL29 is a micronized seaweed cream. This growth promoter is an active ingredient specifically formulated for crop treatments by foliar, hydroponic and/or seed applications. Extracted from marine brown seaweed, issued from Brittany coasts, through Biochemistry in-house technology, TSL29 contains growth hormones, amino acids, betaines, oligosaccharides and essential trace elements. This product is approved for organic agriculture in compliance with regulation (EC) N°834/2007. MA N° 1200295

Rootbooster is a soluble NPK fertilizer for agriculture application made with our seaweed extract, TSL292. Its meticulous in-house formulation ensures 100% solubility and excellent roots and leaves uptake. Rootbooster contains essential minerals and trace-elements. It promotes a strong rooting development, stimulates the plants stress resistance and ensures a better nutrition especially in Phosphorous.

TSL294 - fermented seaweed extract - active ingredient : Because seaweed undergo strong climate stress due to being alternatively exposed to the sun or bad weather and other times, immersed into seawaters, they developed highest quality and active components. TSL294 supplies numerous bio-available trace elements in order to guarantee continuous and sustainable growth. Its high concentration prevents nutritional and physiological imbalance of fruits and vegetables. TSL294 also promotes their size, their conservation and improves impact and bruising resistance.

Boréalg stimulates the physiology of the vine and activates its nutrition thanks to the association of our micronized seaweed extract, TSL292, and Boron. Boréalg homogenizes the flowering of the vine by stimulating its metabolism. This product is approved for organic agriculture in compliance with regulation (EC) N°834/2007.

Pharmaceutical and biotech apparatuses are calculated and manufactured according to your requirements. Stainless steel and special materials are used in the production. After that, the products are grinded, electropolished and tested using non-destructive testing methods, such as ferrite measurements, used for the determination of the ferrite content, or by using the riboflavin test to measure total discharge and CIP/SIP capability. All materials, methods and processes used have been documented in full in detailed QA documents and can be tracked at any time. You can depend on KASAG.

Pressure vessels, reactors, Pharmaceutical and biotech pressure vessles, Process containers, storage tanks, Modules, components, plants, High-pressure apparatuses,Heat exchangers, vaporisers, condensers, Cryo pressure vessels, technologies Nuclear technology, Vacuum chambers, vacuum apparatuses, Columns, according to PED (EN13445 / AD-2000), ASME (U-Stamp), China Stamp (A1), TP TC 032/2013 (EAC) Pharmaceutical and biotech apparatuses are calculated and manufactured according to your requirements. Stainless steel and special materials are used in the production. After that, the products are grinded, electropolished and tested using non-destructive testing methods, such as ferrite measurements, used for the determination of the ferrite content, or by using the riboflavin test to measure total discharge and CIP/SIP capability. All materials, methods and processes used have been documented in full in detailed QA documents and can be tracked at any time. You can depend on KASAG.

We offer TER Floc Vegetalbased flocculants In guaranteed quality, at stable prices and packed appropriately for transportation. Do you need advice on choosing your product or are you looking for a suitable substitution? Our application and product experts are happy to help! Our experience and deep knowledge in the area of specialty chemicals and ingredients ensures that we are well positioned to effectively support both our customers and our suppliers with product and application expertise. Please contact us for more information!

SISTO-SK-i LED Features ● Mounted onto linear actuator up to valve travel of 46 mm ● Continuous valve travel recording via microcontroller ● On-site initialising via magnet or remote initialisation via process control system ● Can be combined with mechanical travel stop ● Remote initialisation possible ● Optical status indication via high-visibility LED ● Electrical connection using 24V M12 plug(s), 8 pin ● Pneumatically connection: M5 internal thread ● Electronic position feedback open/closed ● Error output Variants ● Stainless steel housing ● Plastic housing ● With intergrated solenoid valve; 24V, Low: 0-3V, High: 14 – 24V ● AS-Interface field bus connection

SISTO-CM601 ● Multi-port valve ● Unique design with enclosed diaphragm ● Diaphragm with spiral support starting with size MD65 ● With manual or pneumatic actuator ● Shut-off and sealing to atmosphere by diaphragm, therefore two components in contact with the fluid handled only: body and diaphragm ● Butt weld ends or clamped connection ● Body materials: forged stainless steel and other alloy materials ● Diaphragm materials: EPDM, TFM/EPDM bonded, TFM/EPDM 2-piece ● Available nominal diameters: DN6–DN100 ● Operating temperature: – 20°C to + 160°C ● Permissible operating pressure: vacuum up to 16 barg/ optional 20 barg Benefits: ● Suitable for applications up to a line pressure of 16 barg ● Increased operating reliability ● Self-draining ● No dead volume ● No contamination of fluid handled ● Suitable for CIP/SIP ● Maintenance-free ●Compact, space-saving design

SISTO-CM700 ● Multi-port valve ● Unique design with enclosed diaphragm ● Diaphragm with spiral support starting with size MD65 ● With manual or pneumatic actuator ● Shut-off and sealing to atmosphere by diaphragm, therefore two components in contact with the fluid handled only: body and diaphragm ● Butt weld ends or clamped connection ● Body materials: forged stainless steel and other alloy materials ● Diaphragm materials: EPDM, TFM/EPDM bonded, TFM/EPDM 2-piece ● Available nominal diameters: DN6–DN100 ● Operating temperature: – 20°C to + 160°C ● Permissible operating pressure: vacuum up to 16 barg/ optional 20 barg Benefits: ● Suitable for applications up to a line pressure of 16 barg ● Increased operating reliability ● Self-draining ● No dead volume ● No contamination of fluid handled ● Suitable for CIP/SIP ● Maintenance-free ●Compact, space-saving design

SISTO-C ● Soft-seated shut-off valve ● Unique design with enclosed diaphragm ● Diaphragm with spiral support starting with size MD65 ● With manual or pneumatic actuator ● Shut-off and sealing to atmosphere by diaphragm, therefore two components in contact with the fluid handled only: body and diaphragm ● Body designs: 2-way valve body, T-pattern, tank or multi-port valves ● Butt weld ends or clamped connection ● Drain angle indicated by laser marking ● Body materials: forged stainless steel and other alloy materials ● Diaphragm materials: EPDM, TFM/EPDM bonded, TFM/EPDM 2-piece ● Available nominal diameters: DN 6 – DN 200 ● Operating temperature: – 20°C to + 160°C ● Permissible operating pressure: vacuum up to 16 barg/ optional 20 barg Benefits: ● Suitable for applications up to a line pressure of 16 barg ● Increased operating reliability ● Self-draining ● No dead volume ● No contamination of fluid handled ● Suitable for CIP/SIP ● Maintenance-free

SISTO-C 2-piece TFM/EPDM diaphragms Diaphragms with thicker TFM film are also available for SISTO-C valves. In order that the actuation force can be fully utilised without affecting the plastic diaphragm’s long service life, the TFM diaphragm is backed up by a second diaphragm made of EPDM. A metal pin embedded in the TFM diaphragm helps lifting the diaphragm and thus opens the valve. To avoid damage to the diaphragm during valve closure, the metal pin is fitted to the bonnet assembly by means of a floating nut. Both TFM and EPDM comply with FDA specifications. This 2-piece TFM/EPDM diaphragm is perfectly suited to applica-tions involving high chemical and thermal stress.

SISTO-CBAV ● tank valve ● Unique design with enclosed diaphragm ● Diaphragm with spiral support starting with size MD65 ● With manual or pneumatic actuator ● Shut-off and sealing to atmosphere by diaphragm, therefore two components in contact with the fluid handled only: body and diaphragm ● Body designs: 2-way valve body, T-pattern, tank, multi-port valves ● Butt weld ends or clamped connection ● Drain angle indicated by laser marking ● Body materials: forged stainless steel and other alloy materials ● Diaphragm materials: EPDM, TFM/EPDM bonded, TFM/EPDM 2-piece ● Available nominal diameters: DN6–DN150 ● Operating temperature: – 20°C to + 160°C ● Permissible operating pressure: vacuum up to 16 barg/ optional 20 barg Benefits: ● Suitable for applications up to a line pressure of 16 barg ● Increased operating reliability ● Self-draining ● No dead volume ● No contamination of fluid handled ● Suitable for CIP/SIP ● Maintenance-free ●Compact, space-saving design

SISTO-CM508 ● Multi-port valve ● Unique design with enclosed diaphragm ● Diaphragm with spiral support starting with size MD65 ● With manual or pneumatic actuator ● Shut-off and sealing to atmosphere by diaphragm, therefore two components in contact with the fluid handled only: body and diaphragm ● Butt weld ends or clamped connection ● Body materials: forged stainless steel and other alloy materials ● Diaphragm materials: EPDM, TFM/EPDM bonded, TFM/EPDM 2-piece ● Available nominal diameters: DN6–DN100 ● Operating temperature: – 20°C to + 160°C ● Permissible operating pressure: vacuum up to 16 barg/ optional 20 barg Benefits: ● Suitable for applications up to a line pressure of 16 barg ● Increased operating reliability ● Self-draining ● No dead volume ● No contamination of fluid handled ● Suitable for CIP/SIP ● Maintenance-free ●Compact, space-saving design