United Kingdom
Distributor
United Kingdom
Every freeze-drying formulation has a critical temperature, below which it should be maintained during primary drying in order to prevent processing defects. The Lyostat freeze drying microscope allows observation of the sample structure during drying and heating so that the exact point of collapse can be determined. Innovative lighting and image capture systems (with articulated head for easy sample loading) provide sharp visualisation for easy, accurate identification of structural changes.
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Benchtop Pro are compact research freeze dryers that encompass a range of lab processing requirements.They are flexible, powerful and user-friendly. Condenser temperature options from -55°C to -103°C to enable processing a wide range of products and solvents Extensive range of accessories allows for any shape or size sample to be freeze dried including trays, flasks, ampoules, vials and 96 well microtiter plates Range of manifolds in clear acrylic or stainless steel for superior corrosion resistance Precise vacuum control enables you to achieve better, more repeatable results. One-button auto start-up and shut-down activates all operating parameters in a correct and safe sequence, protecting the product and equipment Hot gas defrost and smooth-walled condensers for fast turnaround and minimal delay between runs
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Highly flexible and with multiple configurations, the Ultra is similar to the Genesis but with expanded capacity to enable those involved in small-scale production or scale-up research to process larger batches. Control options are available to provide cGMP and 21CFR11-compliant data monitoring, security restriction and automation applications, and stainless-steel cleanroom flanging and water cooling can be specified to allow Ultra to be used in controlled environments. The chamber can be isolated so that pressure rise tests can be carried out to give an indication of the end of primary or secondary drying. Additional vacuum gauges and product probes can be specified to provide in-depth process documentation for research or regulatory requirements. Ultra is commonly used by pharmaceutical, biotech and diagnostics companies. With shelf area up to 2.13m2 shelf area and condenser capacity up to 50litres, Ultra is often used for scale-up work and production.
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Unequalled for design and capabilities, the Genesis is the most versatile freeze dryer for pilot, research or small scale production applications. Its advanced product monitoring and process control make it ideal for research and with a user-friendly interface it is perfect for laboratories with multiple products or formulations to investigate. An ergonomic layout allows easy inspection of the vacuum pump and facilitates oil changes, which can be made quickly and cleanly in the laboratory environment. Genesis is available with up to six bulk drying shelves (five vial processing shelves). An expanded range of shelf arrangements, available with a shelf latching kit, allows you to configure it to process a wide variety of vial sizes.
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The Lyostar3 operates a cutting edge R&D system, moving users away from the ‘trial-and-error’ elements during the development processes, toward unique SMART technology that enables fast and easy optimisation of cycles, and ensure the smooth transfer from laboratory- to production-scale. Independent studies have confirmed the use of SMART Freeze Drying Technology™ software from SP Scientific (available with the Lyostar), has offered a time reduction on an average cycle development in the order of 78%. The technology reduces the average cycle development to one or two runs, rather than the conventional series of six to eight runs – thereby not only reducing development time, but also lowering materials costs by at least one third.
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The Emulsiflex range of high pressure homogenisers from Avestin are ideal for a wide range of applications, commonly use d within the pharmaceutical, biotechnology and fine chemicals industries. These include cell lysis, particle size reduction, nanoparticles, emulsions (emulsification), and liposome preparation. Additionally, it offers reliable, consistent processing at adjustable pressures of up to 45,000 psi, Both air-powered and electrically-powered systems are available, and options include filter/extruder attachments, temperature control mechanisms and automatic pressure control. The unique Emulsiflex design ensures that there are no ‘O’-rings or gaskets in the entire path of the product. This means less risk of contamination, easier cleaning and no leakage.
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The Series 3 HT evaporator range from Genevac represents the ultimate in solvent removal technology. Genevac-014 A Solution for High Throughput Evaporation Genevac HT series evaporators are the ideal solution for parallel evaporation bottlenecks in high throughput and production laboratories having high performance and high sample capacities. The unique design of the multi-layer rotor ensures efficient use of valuable laboratory bench space as well as high performance and high throughput evaporation. This proven design has now been updated with the latest version, the Series 3.
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Kinematics & Controls Corporation’s compact modular powder filling systems have proved to be popular in environments where not only precise material dosing is required, but also in areas where companies seek to make the process more efficient, maximising potential product throughputs. Powder is picked up by vacuum and compacted to a constant density within a cylindrical fill chamber. It is subsequently dispensed by the application of low-level, positive-pressure air. The use of a pre-defined vacuum force, compressing the powder sample to a uniform/ even density is the key to achieving the high level of repeat dose accuracy. Cumbersome, time-consuming, hand-weighing is thus eliminated. A wide range of standard gun sizes and filters with various porosities are offered for use with the variety of powders and container sizes which the customer’s process might demand. A custom, 8-up, Micro-Well kit can also be specified, to streamline the filling of 96-cavity well plates.
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Frozen state solutions are a critical product stage or end product in a variety of industries, including freeze drying, pharmaceuticals, food storage and biotech. The Lyotherm3 combines electrical and thermal techniques. This unique dual analysis adds a new dimension to the data of this critical stage. Impedance Analysis (Zsinφ) is a fixed frequency dielectric analysis providing an indication of the sample tracks molecular mobility, including events not picked up by thermal methods like DTA or DSC Differential Thermal Analysis (DTA) measures the difference in temperature between a sample and a reference, highlighting exothermic and endothermic events e.g. crystallisation, eutectic melting and glass transitions Combining DTA and Impedance analysis means Lyotherm is more sensitive to changes within the frozen structure than other exclusively thermal techniques.
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Rocket Synergy 4D is for drying single large volumes of solvent, from a few litres up to approximately 100 litres. The system can also be used for a single batch of up to 5 litres. Rocket Synergy 4D provides fast, safe evaporation for solvents with a boiling point of up to 165°C (DMF) and can easily dry aqueous samples. Automatic evaporation of volumes up to 100 litres Eliminates bumping or foaming Easy vessel manipulation with no glassware to handle Safe, easy product recovery and system cleaning
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Biopharma House
Winnall valley road
SO23 0LD Winchester - United Kingdom
Germany
Dr. Paul Lohmann® offers Magnesium Gluconate as powder, fine powder in food/pharma grade as well as for food supplements. For pharmaceutical applications, it is used for the treatment of hypomagnesemia. For food applications, it is used for magnesium fortification. CAS 3632-91-5 (anh.) EINECS 222-848-2 Dr. Paul Lohmann® carries out product and application development in close cooperation with customers. This includes the adaptation of chemical and physical parameters such as bulk density, wettability, particle size, purity or pH-value.
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Dr. Paul Lohmann® offers Magnesium L-Ascorbate 2-hydrate as powder in food/chem. pure grade as well as for food supplements. For food applications, it is used for magnesium fortification. CAS 15431-40-0 (anh.) EINECS 239-442-6 Dr. Paul Lohmann® carries out product and application development in close cooperation with customers. This includes the adaptation of chemical and physical parameters such as bulk density, wettability, particle size, purity or pH-value.
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Dr. Paul Lohmann® offers Zinc Citrate 3-hydrate as powder, fine powder, micronized powder in food/chem. pure grade as well as for food supplements. For food applications it is used for zinc fortification. CAS 546-46-3 (anh.) EINECS 208-901-2 Dr. Paul Lohmann® carries out product and application development in close cooperation with customers. This includes the adaptation of chemical and physical parameters such as bulk density, wettability, particle size, purity or pH-value.
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Dr. Paul Lohmann® offers Calcium Gluconate 1-hydrate as powder in pharma grade as well as for food supplements. For pharmaceutical applications, it is used for the treatment of hypocalcemia. For food applications, it is used for calcium fortification. CAS 299-28-5 EINECS 206-075-8 Dr. Paul Lohmann® carries out product and application development in close cooperation with customers. This includes the adaptation of chemical and physical parameters such as bulk density, wettability, particle size, purity or pH-value.
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