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  1. RXCHEMLAB

    Germany

    "Fake weed" Synthetic marijuana, often known as K2 or Spice, is a herbal drug sold as incense or smoking material in the United States that is still legal. The goods include one or more synthetic chemicals that operate similarly to & Delta9-tetrahydrocannabinol, or THC, the principal psychoactive ingredient of marijuana. The most prevalent component identified in these items is the eponymous JWH-018, which was initially synthesized by Prof John W Huffman, a well-known Clemson University organic chemist. An analog of CP-47, 497, a cannabinoid produced by Pfizer over 20 years ago, is discovered in Spice products sold in Germany. JWH-018, also known as (1-pentyl-3-(1-naphthoyl)indole) or Naphthalen-1-yl-(1-pentylindol-3-yl)methanone, is one of more than 100 indoles, pyrroles, and indenes created by the Huffman laboratory to develop cannabimimetic, or medications that imitate the action of cannabinoids like T The fundamental purpose of these investigations was to develop pharmacological probes to 1) discover the structure-activity connections of these compounds and 2) elucidate the physiological function of the two subtypes of cannabinoid receptors that humans have: CB1 and CB2.

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