Determination of skin sensitization potential is a critical endpoint in the safety assessment of raw materials, chemicals, mixtures and formulations. Although the Guinea Pig Maximization Test (GPMT) and Local Lymph node assay (LLNA) have historically been used to address this adverse effect, in vitro assays have been developed and validated in order to replace these resource-intensive animal tests. INVITRO-CONNECT GmbH offers various test strategies without animal testing for examining skin sensitization: - Direct Peptide Reactivity Activation Assay (DPRA, OECD 442C) - ARE-Nrf2 Luciferase Keratinocyte Activation Test Method (OECD 442D) -Human Cell Line Activation Test (h-CLAT, OECD 442E) -Kinetic Direct Peptide Reactivity Assay (kDPRA) -Myeloid U937 Skin Sensitization Test (MUSST / U-SENS) -and more Fast Project Execution: personal - competent - reliable --> contact@invitro-connect. - More than 80 Test Laboratories - Product Safety - Regulatory Service -
Germany
Thanks to latest digital technoloy, we can meet your demands at a high professional level. We provide 2D/3D measurement (e.g. dimension measurements, burr measurements, grain size analysis, residual contamination analysis according to ISO 16232 & VDA 19, profile measurements, particle analysis, 3D presentation) with multi-lightning view for various illumination angles, optical shadow effects to clearly identify smallest univenness, reflexion reduction and HDR-view for high colour graduation. Several types of perspectives are possible thanks to a pivoted angle of sight (up to 90°) or by adjusting the mobile object lense (e.g. hollow spaces). We compile a detailed documentation including pictures or videos, where even real-time swivellling views can be recorded. We are looking forward to receiving your enquiry!
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We carry out the following analyses on foodstuffs, organic materials and rinse water. DNA detection We detect the DNA of various plant and animal species for you using real-time PCR. DNA quantification Once a positive detection has been established, the DNA detected can be quantified for both plant and animal species. Meat traceability This test is used to compare the genetic profiles of two samples taken from an animal (for example an ear in the abattoir and meat in the supermarket). This is used to prove whether or not the samples come from the same individual animal. Identification We use sequencing and the bioinformatic analysis of certain genes to identify the bacteria, plant or animal species in a sample.
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