Nucleic acids - Import export

Alpha Lifetech Inc. is a well-recognized leader in the field of single domain antibody discovery. Alpha Lifetech Inc. has developed proprietary procedures for nanobody discovery. Our optimized library construction and screening processes with phage display technology guarantee successful isolation of high affinity camel nanobodies in a short time. We have successfully produced multiple positive clones for a variety of antigens, ranging from large protein molecules (>400kD) to small haptens (small chemical molecules of ~200 dalton), many of the binders have sub-nanomolar affinities measured by ELISA.

Alpha Lifetech Inc. is capable of providing different species or different isotypes of native or synthesized Fab antibody libraries based on our mature phage display technology platform. Building up a high-quality antibody library with a large library size and high diversity has been crucial for the successful isolation of antibodies, it will result in the speed of antibody-drug discovery.

Alpha Lifetech Inc. can offer the antibody affinity maturation service by using mutation and selection technologies. We usually use scFv as the antibody format in the processes of affinity maturation service and a monovalent display phagemid system which has been used to reduce the avidity effects during antigen-binding screening. Our professional team can provide affinity maturation services for single-domain antibodies as well.