Pharmaceutical products - Import export

Clofazimin is considered one of the cationic amphiphic medicines. The mechanism of action is not fully understood. Clofamizin is a red dye that has a bacteriostatic effect on the leprosy causing mycobacterium leprae. The active ingredient is used by WHO to treat leprosy.

Zofenopril calcium is an inhibitor of the angiotensin-converting enzyme (ACE inhibitor). Angiotensin I & II control the tone of the blood vessels and are part of the Renin Angiotensin aldosterone system. The increase in angiotensin II leads to a reduction in vascular tone, which leads to lower blood pressure. Therefore, it is used in the therapy of arterial hypertension and acute heart attacks.

Diethylpropion hydrochloride is an amphetamine derivative that acts systemically on the cardiovascular system, certain organs and the brain (or CNS) as an indirect α-sympathomimetic. It is counted among the psychostimulants and suppresses needs such as sleep, appetite, thirst and urination. The release of catecholamines (e.g. adrenaline, dopamine) increases heart rate, blood pressure and pulmonary circulation. It is used to treat obesity.

Warfarin Sodium, amorphous is a synthetically synthesized Active Pharmaceutical Ingredient, produced under cGMP, compliant with EP monograph. Its CAS-N° reads [129-06-6]. It is used to treat or prevent blood clots in veins or arteries, which can reduce the risk of stroke, heart attack, or other serious conditions. Detailed specification, Certificate of Analysis and samples are available on request. Warfarin sodium is a 4-hydroxycumarin, these are known as vitamin K antagonists. Vitamin K antagonists are anticoagulants that encroach on the blood clotting cascade. Since the substance can have significant fluctuations in its effectiveness, depending on the genotype, the blood clotting levels for dose tuning should be tested regularly.

Crotamiton is an active pharmaceutical ingredient produced under cGMP. * only European manufacturer * competitive process * up-to-date documentation * starting materials sourced from EU (no dependence on China) Crotamitone is an antipruriginosum used to treat burial mites (scabies). It works against the mites themselves, but also against the itching.

Sodium Borohydride is a versatile and selective reducing agent that has a variety of applications in manufacturing of pharmaceutical active ingredients, crop protection agents, aroma compounds and other fine chemicals. Its CAS-N° reads [16940-66-2]. Typical applications are: Reduction of Aldehydes / Acid Chlorides / Anhydrides to primary Alcohols; Reduction of Ketones to secondary Alcohols; Reduction of Imines to Amines; Removing impurities and purification of process streams; Metal ion reduction / Noble metal recovery / Dehalogenations. Sodium Borohydride is due to its reactivity a hazardous compound under dangerous goods regulation which requires specific storage. Our material is usually promptly available from stock for industrial consumers, To influence reactivity and handling comfort the product is available as coarse powder, fine powder and as granules. Detailed specification, material safety data sheet and additional documents are available on request.

Pipamperone 2HCl is an active pharmaceutical ingredient manufactured following the EU-GMP regulations. We offer the API following EU-GMP (ICH Q7) regulations with an active ASMF. Material is availalbe upon request from stock. The active ingredient is used as an antipsychotic and sedative. It works mainly on the serotonin and dopamine receptors. The sedative effect outweighs that of the antipsychotic. Pipamperone regulates internal restlessness, sleep disturbances, and also weakens arousal conditions, as well as aggressiveness.

Ketoprofen is a synthetically synthesized Active Pharmaceutical Ingredient, produced under cGMP, compliant with EP, JP monographs. Its CAS-N° reads 22071-15-4. It is used in treatment of arthritis-related inflammatory pains, severe toothaches that result in the inflammation of the gums or nerve pain. Ketoprofen is an acidic, non-opioid analgesic used for pain and inflammation. By inhibiting prostaglandin synthesis at the key enzyme cyclooxygenase, it can be used for acute and chronic pain (e.g. arthrosis and arthritides). Like most active ingredients in its class, it is poorly tolerated by the gastrointestinal tract, a particular side effect is light sensitization. Detailed specification, Certificate of Analysis and samples are available on request.

Doxazosin Mesylate is a synthetically synthesized Active Pharmaceutical Ingredient, produced under cGMP, compliant with EP monograph. Its CAS-N° reads 77883-43-3. It is used to treat high blood pressure and urinary retention associated with benign prostatic hyperplasia - BPH. Doxazosin mesylate is a selective α-blocker that selectively binds to α1-receptors, thus dilating peripheral blood vessels. This reduces blood pressure and cholesterol levels of the serum. Detailed specification, Certificate of Analysis and samples are available on request.

Trospium chloride is a synthetic API, produced under cGMP. Its quality complies with International Monographs such as European Pharmacopoeia (EP) or US-Pharmacopoeia (USP). CAS number is [10405-02-4]. Trospium chloride is a tropane derivative (3α-nortropanol benzene acid ester) and an anticholinergic agent. This is used to treat urge and reflex incontinence. This is achieved by the competitive blockage of acetylcholine on their receptors. This inhibits the parasympathetic influence, smooth muscles, heart muscle and parts of the peripheral nervous system. Detailed specification, certificates of analysis and samples are available on request.

Propofol belongs to the group of phenol derivatives. The active substance is a short-acting anesthetic. It is used for the initiation and maintenance of intravenous anesthesia.

Enzalutamide binds to androgen receptors and thereby inhibits them (antiandrogen). In addition, translocation in the cell nuclei is inhibited and the binding to the DNA is weakened, as well as the recruitment of cofactors for transcription. This leads to the inhibition of gene expression, which are regulated by the androgen receptors. Due to the triple mechanism of action, Enzalutamide differs from the usual anti-androgenic substances. Due to its anti-androgenic properties, the active ingredient also has an antineoplastic effect in androgen-sensitive tumors (e.g. metastatic prostate cancer).

Doxapram hydrochloride is a synthetically synthesized Active Pharmaceutical Ingredient, produced under cGMP, compliant with EP, USP, JP, ANVISA monographs. Its CAS-N° reads 7081-53-0. It is used in intensive care settings to stimulate the respiratory rate in patients with respiratory failure. It may be useful for treating respiratory depression in patients who have taken excessive doses of specific other drugs. Detailed specification, Certificate of Analysis and samples are available on request.

Pentafluorobenzene belongs to the group of benzene derivatives. The intermediate is used in Agro, Electronics, Fine Chemicals, Perfumery, Pharma & Veterinary.

Ethacridine lactate is an aromatic organic compound based on acridine. It is mainly used as an antiseptic (in the form of ointments and solutions) for the treatment of infected wounds and pyoderma. Besides, it finds application as bladder and vaginal irrigation solution. It is effective against most gram-positive bacteria, such as streptococci and staphylococci, but ineffective against gram-negative bacteria, such as Pseudomonas aeruginosa. In addition, ethacridine lactate is used for diarrhea (or diarrhea prophylaxis). Here, the active ingredient normalizes the increased movement of the intestines through its antispasmodic effect. It also has an antibacterial effect and reduces the permeability of the intestinal wall to fluids. Thus, diarrhea can be counteracted. As a rule, it is administered in combination with tannin albuminate.

Bamipine is an anti-allergic and antipruritic agent from the group of 1st generation antihistamines, which is used in the form of a gel for the symptomatic treatment of insect bites. The anticholinergic effects are based on antagonism at histamine H1 receptors. The drug, administered as a gel, is applied thinly several times a day. In addition, the cooling effect thus mediated alleviates the discomfort caused by insect bites.

Trifluoroacetic acid ethyl ester belongs to the group of acetic acid derivatives. The intermediate is used in the Agro, Electronics, Fine Chemicals, Perfumery, Pharma & Veterinary industries. It is used in the production of Celecoxib, Efavirenz, Lisinopril & Sitagliptin phosphate

Pentafluorobenzonitrile belongs to the group of benzene derivatives. The intermediate is used in the Agro, Electronics, Fine Chemicals, Perfumery, Pharma, Veterinary industry.

4’-(Methyl­mercapto)-aceto­phenone belongs to the group of acetophenone derivatives. The intermediate is used in pharma, agro & electro and applied in the production of Elafibranor, Rofecoxib & Saroglitazar.

Methanesulfonyl chloride belongs to the group of methanesulfonic acid derivatives. The intermediate is used in Agro, Electronics, Fine Chemicals, Perfumery, Pharma & Veterinary.

Epiandrosterone belongs to the group of steroid hormone derivatives. The intermediate is used in the pharmaceutical industry. It is a building block of Estrone.

1-Piperazinoethanol belongs to the group of piperazine derivatives. The intermediate is used in the pharmaceutical industry for example for Acetophenazine, Carfenazine, Cetirizine, Clopenthixol, Dasatinib, Flupentixol.

N-ethylpiperazine belongs to the group of piperazine derivatives. The intermediate is used in the Pharma, Agro & Fine Chemicals Industry. It is used for the production of Abemaciclib, Blonaserin, Piperazine & Vardenafil.

4,6-Dichloro-5-nitro-2-(propylthio)-pyrimidine belongs to the group of pyrimidine derivatives. The intermediate is used in the pharmaceutical industry as building block for example of Ticagrelor.

Brompentafluorobenzene belongs to the group of benzene derivatives. The intermediate is used in the Agro, Electronics, Fine Chemicals, Perfumery, Pharma and Veterinary industry.

Trifluoroacetic acid methyl ester belongs to the group of acetic acid derivatives. The intermediate is used in the Agro, Electronics, Fine Chemicals, Perfumery, Pharma & Veterinary industry.

Trifluoroacetic anhydride belongs to the group of acetic acid derivatives. The intermediate is used in the Agro, Electronics, Fine Chemicals, Perfumery, Pharma & Veterinary industries. It is applied in the production of Tadalafil, Tapentadol & Vildagliptin

Piperazine belongs to the group of nitrogen heterocycles. The Intermediate is used in the pharmaceutical industry for example for Ciprofloxacin, Doxazosin, Quetiapin & Terazosin.

Potassium borohydride belongs to the group of complex salts. The Intermediate is used in the Agro, Electronics, Fine Chemicals, Pharma, Pulp & Paper industry.